Myelopoiesis is regulated by osteocytes through Gsα-dependent signaling

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    • Abstract:
      Key PointsDeletion of Gsα in osteocytes induces severe osteopenia and a dramatic expansion of cells of the myeloid lineage.Osteocytes regulate hematopoiesis and specifically contribute to myelopoiesis by secreting proliferative factors such as G-CSF.