The Utility of Neutrophil-to-Lymphocyte Ratio as a Severity Predictor of Acute Appendicitis, Length of Hospital Stay and Postoperative Complication Rates.

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  • Additional Information
    • Publication Year:
      2015
    • Author-Supplied Keywords:
      Appendicitis
      Neutrophil-to-lymphocyte ratio
      Postoperative outcomes
    • Abstract:
      Background: Numerous screening tools have been reported to aid in diagnosing appendicitis, but have poor severity prediction and lack accurate estimation of postoperative complications or total length of hospital stay (LOS). Aim: This study aims at evaluating the utility of neutrophil-to-lymphocyte (NLR) ratio in predicting the severity of appendicitis, LOS and 30-day complication rates. Methods: Patients who underwent appendicectomy over a 4-year period were evaluated. Demographics, blood results, severity of appendicitis, LOS and 30-day complications were recorded. Recommended cut-off values of NLR and C-reactive protein (CRP) for severity of appendicitis were determined using receiver operating characteristic analysis. The Mann-Whitney test was performed to assess the correlations between LOS and 30-day complications with NLR. Results: A total of 663 patients were included in the study of which 57.3% (n = 380) were male with mean patient age of 23.6 years, and 461 appendix specimens (69.6%) had simple inflammation on histological evaluation. A NLR of >6.35 or CRP of >55.6 were statistically associated with severe acute appendicitis, with a median of one extra hospital day admission (p < 0.0001). Mean NLR was statistically higher in patients with postoperative co(13.69 for severe vs. 7.29 for simple appendicitis group, p = 0.016). Conclusion: We advocate that NLR is a useful adjunct in predicting severity of appendicitis. It aids in delineating severe inflammation requiring surgery without substantial delay. © 2015 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
    • Abstract:
      Copyright of Digestive Surgery is the property of Karger AG and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
    • ISSN:
      02534886
    • Accession Number:
      111356371
  • Citations
    • ABNT:
      KELLY, M. E. et al. The Utility of Neutrophil-to-Lymphocyte Ratio as a Severity Predictor of Acute Appendicitis, Length of Hospital Stay and Postoperative Complication Rates. Digestive Surgery, [s. l.], v. 32, n. 6, p. 459, 2015. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=111356371&custid=s6224580. Acesso em: 4 jun. 2020.
    • AMA:
      Kelly ME, Khan asif, Riaz M, et al. The Utility of Neutrophil-to-Lymphocyte Ratio as a Severity Predictor of Acute Appendicitis, Length of Hospital Stay and Postoperative Complication Rates. Digestive Surgery. 2015;32(6):459. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=111356371&custid=s6224580. Accessed June 4, 2020.
    • APA:
      Kelly, M. E., Khan, asif, Riaz, M., Bolger, J. C., Bennani, F., Khan, W., Waldron, R., Khan, I. Z., & Barry, K. (2015). The Utility of Neutrophil-to-Lymphocyte Ratio as a Severity Predictor of Acute Appendicitis, Length of Hospital Stay and Postoperative Complication Rates. Digestive Surgery, 32(6), 459.
    • Chicago/Turabian: Author-Date:
      Kelly, Michael E., asif Khan, Mudassar Riaz, Jarlath C. Bolger, Fidal Bennani, Waqar Khan, Ronan Waldron, Iqbal Z. Khan, and Kevin Barry. 2015. “The Utility of Neutrophil-to-Lymphocyte Ratio as a Severity Predictor of Acute Appendicitis, Length of Hospital Stay and Postoperative Complication Rates.” Digestive Surgery 32 (6): 459. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=111356371&custid=s6224580.
    • Harvard:
      Kelly, M. E. et al. (2015) ‘The Utility of Neutrophil-to-Lymphocyte Ratio as a Severity Predictor of Acute Appendicitis, Length of Hospital Stay and Postoperative Complication Rates’, Digestive Surgery, 32(6), p. 459. Available at: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=111356371&custid=s6224580 (Accessed: 4 June 2020).
    • Harvard: Australian:
      Kelly, ME, Khan, asif, Riaz, M, Bolger, JC, Bennani, F, Khan, W, Waldron, R, Khan, IZ & Barry, K 2015, ‘The Utility of Neutrophil-to-Lymphocyte Ratio as a Severity Predictor of Acute Appendicitis, Length of Hospital Stay and Postoperative Complication Rates’, Digestive Surgery, vol. 32, no. 6, p. 459, viewed 4 June 2020, .
    • MLA:
      Kelly, Michael E., et al. “The Utility of Neutrophil-to-Lymphocyte Ratio as a Severity Predictor of Acute Appendicitis, Length of Hospital Stay and Postoperative Complication Rates.” Digestive Surgery, vol. 32, no. 6, Dec. 2015, p. 459. EBSCOhost, search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=111356371&custid=s6224580.
    • Chicago/Turabian: Humanities:
      Kelly, Michael E., asif Khan, Mudassar Riaz, Jarlath C. Bolger, Fidal Bennani, Waqar Khan, Ronan Waldron, Iqbal Z. Khan, and Kevin Barry. “The Utility of Neutrophil-to-Lymphocyte Ratio as a Severity Predictor of Acute Appendicitis, Length of Hospital Stay and Postoperative Complication Rates.” Digestive Surgery 32, no. 6 (December 2015): 459. http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=111356371&custid=s6224580.
    • Vancouver/ICMJE:
      Kelly ME, Khan asif, Riaz M, Bolger JC, Bennani F, Khan W, et al. The Utility of Neutrophil-to-Lymphocyte Ratio as a Severity Predictor of Acute Appendicitis, Length of Hospital Stay and Postoperative Complication Rates. Digestive Surgery [Internet]. 2015 Dec [cited 2020 Jun 4];32(6):459. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edb&AN=111356371&custid=s6224580