Atrial septal defect and exercise capacity: value of cardiopulmonary exercise test in assessment and follow-up.

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  • Additional Information
    • Affiliation:
      Paediatric and Adult Congenital Cardiology Department, M3C Regional Reference CHD Centre, University Hospital, Montpellier, France
      Physiology and Experimental Biology of Heart and Muscles Laboratory-PHYMEDEXP, UMR CNRS 9214, INSERM U1046, University of Montpellier, Montpellier, France
      Functional Exploration Laboratory, Physiology Department, University Hospital, Montpellier, France
      Paediatric Cardiology and Rehabilitation Unit, St-Pierre Institute, Palavas-Les-Flots, France
    • Subject Terms:
    • Subject Terms:
    • Abstract:
      Nearly four decades ago, the World Health Organization stated that functional capacity explorations best reflected the impact of a chronic disease on quality of life. Today, cardio-pulmonary exercise test (CPET) is recommended in the follow-up of patients with congenital heart diseases (CHDs). Indeed, the maximum oxygen uptake (VO2max) and the ventilatory efficiency (VE/VCO2 slope) correlate with both the prognosis and the quality of life in this population. Atrial septal defects (ASDs) represent the second most frequent CHD and are usually considered as simple CHDs. However, the exercise capacity of ASD patients may be impaired. Therefore, the CPET provides important information in assessment and follow- up of patients with ASDs, for both children and adults. Exercise capacity of patients with unrepaired ASDs depends on the importance of the shunt, the right ventricular (RV) function and volume overload, the level of pulmonary arterial pressure, and the occurrence of arrhythmias. For repaired ASDs, exercise capacity also depends on the delay before closure and the type of procedure (catheter or surgery). In most cases, the exercise capacity is nearly normal and CPET contributes to promote sports participation. In addition, a regular CPET follow-up is necessary to evaluate the occurrence, severity and physiological mechanisms of comorbidities, i.e., heart failure, pulmonary hypertension and arrhythmia. Furthermore, CPET follow-up in patients with ASDs may detect early onset of muscular deconditioning, for which cardiac rehabilitation may be considered.
    • Journal Subset:
      Asia; Biomedical; Peer Reviewed
    • Special Interest:
      Evidence-Based Practice
    • ISSN:
      2072-1439
    • MEDLINE Info:
      NLM UID: 101533916
    • Publication Date:
      20181228
    • Publication Date:
      20190513
    • Accession Number:
      http://dx.doi.org/10.21037/jtd.2017.11.30
    • Accession Number:
      133718217
  • Citations
    • ABNT:
      AMEDRO, P. et al. Atrial septal defect and exercise capacity: value of cardiopulmonary exercise test in assessment and follow-up. Journal of Thoracic Disease, [s. l.], v. 10, p. S2864–S2873, 2018. DOI 10.21037/jtd.2017.11.30. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=ccm&AN=133718217&custid=s6224580. Acesso em: 18 fev. 2020.
    • AMA:
      Amedro P, Guillaumont S, Bredy C, Matecki S, Gavotto A. Atrial septal defect and exercise capacity: value of cardiopulmonary exercise test in assessment and follow-up. Journal of Thoracic Disease. 2018;10:S2864-S2873. doi:10.21037/jtd.2017.11.30.
    • APA:
      Amedro, P., Guillaumont, S., Bredy, C., Matecki, S., & Gavotto, A. (2018). Atrial septal defect and exercise capacity: value of cardiopulmonary exercise test in assessment and follow-up. Journal of Thoracic Disease, 10, S2864–S2873. https://doi.org/10.21037/jtd.2017.11.30
    • Chicago/Turabian: Author-Date:
      Amedro, Pascal, Sophie Guillaumont, Charlene Bredy, Stefan Matecki, and Arthur Gavotto. 2018. “Atrial Septal Defect and Exercise Capacity: Value of Cardiopulmonary Exercise Test in Assessment and Follow-Up.” Journal of Thoracic Disease 10 (September): S2864–73. doi:10.21037/jtd.2017.11.30.
    • Harvard:
      Amedro, P. et al. (2018) ‘Atrial septal defect and exercise capacity: value of cardiopulmonary exercise test in assessment and follow-up’, Journal of Thoracic Disease, 10, pp. S2864–S2873. doi: 10.21037/jtd.2017.11.30.
    • Harvard: Australian:
      Amedro, P, Guillaumont, S, Bredy, C, Matecki, S & Gavotto, A 2018, ‘Atrial septal defect and exercise capacity: value of cardiopulmonary exercise test in assessment and follow-up’, Journal of Thoracic Disease, vol. 10, pp. S2864–S2873, viewed 18 February 2020, .
    • MLA:
      Amedro, Pascal, et al. “Atrial Septal Defect and Exercise Capacity: Value of Cardiopulmonary Exercise Test in Assessment and Follow-Up.” Journal of Thoracic Disease, vol. 10, Sept. 2018, pp. S2864–S2873. EBSCOhost, doi:10.21037/jtd.2017.11.30.
    • Chicago/Turabian: Humanities:
      Amedro, Pascal, Sophie Guillaumont, Charlene Bredy, Stefan Matecki, and Arthur Gavotto. “Atrial Septal Defect and Exercise Capacity: Value of Cardiopulmonary Exercise Test in Assessment and Follow-Up.” Journal of Thoracic Disease 10 (September 2, 2018): S2864–73. doi:10.21037/jtd.2017.11.30.
    • Vancouver/ICMJE:
      Amedro P, Guillaumont S, Bredy C, Matecki S, Gavotto A. Atrial septal defect and exercise capacity: value of cardiopulmonary exercise test in assessment and follow-up. Journal of Thoracic Disease [Internet]. 2018 Sep 2 [cited 2020 Feb 18];10:S2864–73. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=ccm&AN=133718217&custid=s6224580