Pulmonary rehabilitation in patients with an acute exacerbation of chronic obstructive pulmonary disease.

Item request has been placed! ×
Item request cannot be made. ×
  Processing Request
  • Additional Information
    • Affiliation:
      Harefield Pulmonary Rehabilitation and Muscle Research Laboratory, Royal Brompton and Harefield NHS Foundation Trust, UK
      National Heart and Lung Institute, Imperial College, London, UK
      King's College London, Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, London, UK
    • Subject Terms:
    • Subject Terms:
    • Abstract:
      Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are one of the most common causes of emergency hospital admission and place great burden upon healthcare systems. Furthermore, AECOPD represent an important life event for patients, and are associated with significant reductions in physical activity, skeletal muscle function, exercise tolerance and health-related quality of life. Pulmonary rehabilitation, an intervention comprising supervised exercise-training and education, may counteract these negative consequences and target modifiable risk factors for hospital readmission. A recent Cochrane systematic review included 20 randomized controlled trials comparing pulmonary rehabilitation after exacerbation of COPD versus conventional care. Overall, the evidence supports moderate to large effects on health-related quality of life and exercise capacity. However, there is substantial heterogeneity across studies, and more recent studies have been more equivocal, including around hospital readmissions, particularly when rehabilitation is started in the inpatient setting. In this narrative review, we examine the rationale for pulmonary rehabilitation following AECOPD with a particular focus on skeletal muscle function, review the current evidence for pulmonary rehabilitation in the AECOPD setting, and identify areas that require future research, including the structure and nature of the intervention, improving uptake and adherence, and the role of alternative rehabilitation strategies for patients with AECOPD.
    • Journal Subset:
      Asia; Biomedical; Peer Reviewed
    • ISSN:
      2072-1439
    • MEDLINE Info:
      NLM UID: 101533916
    • Publication Date:
      20180914
    • Publication Date:
      20180914
    • Accession Number:
      http://dx.doi.org/10.21037/jtd.2018.03.18
    • Accession Number:
      131651184
  • Citations
    • ABNT:
      JONES, S. E. et al. Pulmonary rehabilitation in patients with an acute exacerbation of chronic obstructive pulmonary disease. Journal of Thoracic Disease, [s. l.], v. 10, p. S1390–S1399, 2018. Disponível em: . Acesso em: 19 nov. 2019.
    • AMA:
      Jones SE, Barker RE, Nolan CM, Patel S, Maddocks M, Man WDC. Pulmonary rehabilitation in patients with an acute exacerbation of chronic obstructive pulmonary disease. Journal of Thoracic Disease. 2018;10:S1390-S1399. doi:10.21037/jtd.2018.03.18.
    • APA:
      Jones, S. E., Barker, R. E., Nolan, C. M., Patel, S., Maddocks, M., & Man, W. D. C. (2018). Pulmonary rehabilitation in patients with an acute exacerbation of chronic obstructive pulmonary disease. Journal of Thoracic Disease, 10, S1390–S1399. https://doi.org/10.21037/jtd.2018.03.18
    • Chicago/Turabian: Author-Date:
      Jones, Sarah E., Ruth E. Barker, Claire M. Nolan, Suhani Patel, Matthew Maddocks, and William D. C. Man. 2018. “Pulmonary Rehabilitation in Patients with an Acute Exacerbation of Chronic Obstructive Pulmonary Disease.” Journal of Thoracic Disease 10 (May): S1390–99. doi:10.21037/jtd.2018.03.18.
    • Harvard:
      Jones, S. E. et al. (2018) ‘Pulmonary rehabilitation in patients with an acute exacerbation of chronic obstructive pulmonary disease’, Journal of Thoracic Disease, 10, pp. S1390–S1399. doi: 10.21037/jtd.2018.03.18.
    • Harvard: Australian:
      Jones, SE, Barker, RE, Nolan, CM, Patel, S, Maddocks, M & Man, WDC 2018, ‘Pulmonary rehabilitation in patients with an acute exacerbation of chronic obstructive pulmonary disease’, Journal of Thoracic Disease, vol. 10, pp. S1390–S1399, viewed 19 November 2019, .
    • MLA:
      Jones, Sarah E., et al. “Pulmonary Rehabilitation in Patients with an Acute Exacerbation of Chronic Obstructive Pulmonary Disease.” Journal of Thoracic Disease, vol. 10, May 2018, pp. S1390–S1399. EBSCOhost, doi:10.21037/jtd.2018.03.18.
    • Chicago/Turabian: Humanities:
      Jones, Sarah E., Ruth E. Barker, Claire M. Nolan, Suhani Patel, Matthew Maddocks, and William D. C. Man. “Pulmonary Rehabilitation in Patients with an Acute Exacerbation of Chronic Obstructive Pulmonary Disease.” Journal of Thoracic Disease 10 (May 3, 2018): S1390–99. doi:10.21037/jtd.2018.03.18.
    • Vancouver/ICMJE:
      Jones SE, Barker RE, Nolan CM, Patel S, Maddocks M, Man WDC. Pulmonary rehabilitation in patients with an acute exacerbation of chronic obstructive pulmonary disease. Journal of Thoracic Disease [Internet]. 2018 May 3 [cited 2019 Nov 19];10:S1390–9. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=ccm&AN=131651184&custid=s6224580