ULTRAZVUČNI SKRINING KARCINOMA ENDOMETRIJUMA KOD ŽENA U POSTMENOPAUZI BEZ SIMPTOMA.

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    • Alternate Title:
      ULTRASOUND IN SCREENING OF ENDOMETRIAL CARCINOMA IN ASYMPTOMATIC POSTMENOPAUSAL WOMEN.
    • Abstract:
      Introduction The aim of this prospective study was to investigate whether there was a significant difference in ultrasound detection of pathologic states of endometrium between asymptomatic postmenopausal women and postmenopausal women with uterine bleeding in whom the thickness of endometrium was greater than 3 mm at ultrasound examination. Material and methods The study included 128 postmenopausal women with uterine bleeding and 29 asymptomatic posmenopausal women who underwent gynecological examination, transvaginal ultrasound examination, fractional explorative curettage and histopathological examination of the endometrium. Results The results showed no statistically significant difference between the examined groups of women in relation to the detection of pathologic states of the endometrium (polyps, hyperplasias and carcinomas) as well as between individual pathologic states, although the research showed that the asymptomatic women were more frequently presented with well-differentiated carcinoma versus the medium-differentiated carcinoma in the symptomatic group of women. Conclusion It can be concluded that the transvaginal ultrasound examination in postmenopausal women could be an adequate screening method for detection of endometrial carcinoma in early asymptomatic stage of the disease, whereas in the women with ultrasound finding of the thickened endometrium, the final diagnosis should be established by histopathological examination of the endometrium samples obtained by hysteroscopy, instead of previously used explorative curettage. [ABSTRACT FROM AUTHOR]
    • Abstract:
      Cilj ove prospektivne studije bio je da ultrazvukom utvrdimo da li postoje značajne razlike u otkrivanju patoloških promena endometrijuma kod žena u postmenopauzi i žena u postmenopauzi sa materičnim krvarenjem, kod kojih je transvaginalnim ultrazvučnim pregledom izmeren endometrijum deblji od 3 mm. Ispitivanje je obuhvatilo 128 žena u postmenopauzi sa materičnim krvarenjem i 29 žena bez simptoma u postmenopauzi kod kojih je urađen ginekološki pregled, transvaginalni ultrazvučni pregled, frakcionirana eksplorativna kiretaža i patohistološki pregled endometrijuma. Nismo dobili statistički značajne razlike između ispitivanih grupa žena u pogledu otkrivanja svih patoloških promena endometrijuma zajedno (polipa, hiperplazija i karcinoma), kao ni svake od ovih patoloških promena pojedinačno, ali smo uočili da su karcinomi otkriveni kod žena bez simptoma češće bili dobro di-ferentovani, a kod žena sa simptomima srednje diferentovani. Zaključujemo da bi transvaginalni ultrazvučni pregled kod žena u postmenopauzi mogao da bude dobra skrining metoda za otkrivanje karcinoma endometrijuma u ranoj, asimptomatoskoj fazi bolesti, a da bi kod žena sa ultrazvučno zadebljalim endometrijumom definitivnu dijagnozu trebalo postaviti patohistološkim pregledom endometrijuma dobijenog histeroskopijom, umesto ranije korišćene eksplorativne kiretaže. [ABSTRACT FROM AUTHOR]
    • Abstract:
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