The article evaluates the scientific literature on currently available medical treatments for erectile dysfunction (ED): penile implants, vascular surgery, intracavernosal injections, vacuum erection devices, penile support sleeve, intraurethral suppositories and oral/topical treatments. Erectile dysfunction (ED) is defined as the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual activity. ED affects men in all age groups. However, ED is more prevalent among older men, and the likelihood of persistent erectile difficulties increases with age. There are a wide variety of organic, as well as psychogenic causes of ED. Use of certain hypotensive and psychotropic drugs, can lead to ED. At present majority of ED cases are supposed to be organic in origin. The rapid growth in our awareness and understanding of the prevalence and pathophysiology of ED has intensified the search for safe, effective, and cost- efficient medical treatments. It is felt that since no treatment method is safe and effective for all men with ED, the clinician must carefully evaluate the nature of each man's ED, be familiar with the various treatment options, and carefully explain the advantages and disadvantages of various approaches to the patient.